http://www.youtube.com/watch?v=rWIfC-9cijk
During the first season of Pee-Wee’s Playhouse, a trio of kids were cast on the show called the “Playhouse Gang”, who popped up in six episodes to interact with Pee-Wee. At the age of seven, Natasha Lyonne made her acting debut as “Opal”, one of the members of the Playhouse Gang. As a bonus, here’s webcam footage of Natasha watching the very same Pee-Wee’s Playhouse clip from above and giving off her live reaction.
http://www.youtube.com/watch?v=23nRCKp1FwQ